Carboplatin plus cytarabine in the treatment of high-risk acute myeloblastic leukemia
نویسندگان
چکیده
منابع مشابه
Treatment of adult acute myeloblastic leukemia.
The introduction of combination chemotherapy in the treatment of adult acute leukemia has had a profound impact on the response and duration of survival of patients with adult acute myeloblastic leukemia. In the past decade, the combination of cytosine arabinoside with an anthracycline antibiotic, either daunorubicin, adriamycin, or rubidazone, has been responsible to a large degree for the suc...
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BACKGROUND In order to assess the role of the combination of low-dose cytarabine (Ara-C) plus aclarubicin (CA) in remission induction for patients with untreated acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS), we retrospectively analyzed the efficacy and safety of CA. PATIENTS AND METHODS Data of twenty patients with untreated AML or high-risk MDS who were ineligible...
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We are writing to clarify the interpretation of results contained within a paper by Giles et al.1 In their abstract, the authors state, “The [complete remission] CR rate was significantly higher for the laromustine/[high-dose cytarabine] HDAC group (35% vs 19%, P .005). However, the 30-day mortality rate and median progression-free survival were significantly worse in this group compared with H...
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A correlation was made between chromosomal findings in the marrow of AML patients obtained during the course of the disease, some of the clinical and cytologic features, and the survival span of these patients. The median survival time for each patient was obtained by the use of log-probability paper. Of the 69 patients with AML studied, 29 showed abnormal metaphases in the marrow at least once...
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ژورنال
عنوان ژورنال: Leukemia
سال: 1999
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2401278